The stakes are high for both of these clubs, but for very different reasons.
Liverpool are currently third in the table, two points behind Man United and two points ahead of Spurs. Meanwhile Crystal Palace are just two points above the relegation zone, and the battle to survive is really tight.
Also on the box today are high-riding Man City, who are away to mid-table Everton; while in the Championship Aston Villa will be trying to secure their play-off spot against struggling Hull City; and north of the border second-place Rangers are away to Motherwell.
Crystal Palace v Liverpool is on Sky Sports Main Event and Sky Premier League at 11.30 (kick-off 12.30).
Motherwell v Rangers is on BT Sport 1 at 12.00 (kick-off 12.45).
Everton v Manchester City is on BT Sport 1 at 17.00 (kick-off 17.30).
Hull City v Aston Villa is on Sky Sports Main Event and Sky Football at 17.15 (kick-off 17.30).